The External Interrupt Controller (EIC) allows external pins to be configured as interrupt lines. Each interrupt line can be individually masked and can generate an interrupt on rising, falling, or both edges, or on high or low levels. Each external pin has a configurable filter to remove spikes. Each external pin can also be configured to be asynchronous in order to wake up the device from sleep modes where all clocks have been disabled. External pins can also generate an event. Each external pin can be defined as secured or non-secured, where secured pins can only be handled by secure accesses.

A separate non-maskable interrupt (NMI) is also supported. It has properties similar to the other external interrupts, but is connected to the NMI request of the CPU, enabling it to interrupt any other interrupt mode.