When INTFLAG.SB is set, the I2C host will already have received one data packet. The I2C host must respond by sending either an ACK or NACK. Sending a NACK may be unsuccessful when arbitration is lost during the transmission. In this case, a lost arbitration will prevent setting INTFLAG.SB. Instead, INTFLAG.MB will indicate a change in arbitration. Handling of lost arbitration is the same as for data bit transmission.