33.6.14 Sleep Mode Operation
The Run in Standby bit in the Control A register (CTRLA.RUNSTDBY) controls the behavior of the ADC during standby sleep mode. When CTRLA.RUNSTDBY=0, the ADC is disabled during sleep, but maintains its current configuration. When CTRLA.RUNSTDBY=1, the ADC continues to operate during sleep. Note that when CTRLA.RUNSTDBY=0, the analog blocks are powered off for the lowest power consumption. This necessitates a start-up time delay when the system returns from sleep.
When CTRLA.RUNSTDBY=1, any enabled ADC interrupt source can wake up the CPU, except the OVERRUN interrupt.. While the CPU is sleeping, ADC conversion can only be triggered by events.