| TWI | Normal/Fast (Client/Host)/FM+ | x | x | x | x | x | x | x | x | x | x | x |
| Alternate command | x | x | x | x | x | x | x | x | x | x | x |
| 3 Client ADDR | x | x | x | x | x | x | x | x | x | x | x |
| High-speed | x | x | x | x | x | x | x | x | x | x | x |
| SMBUS | x | x | x | x | x | x | x | x | x | x | x |
| Sniffer | x | x | x | x | x | x | x | x | x | x | x |
| Asynchronous partial wake-up | x | x | x | x | x | x | x | x | x | x | x |
| FIFO size: 32 bytes | x | x | x | x | x | x | x | x | x | x | x |
| USART | Basic | x | x | x | x | x | x | x | x | x | x | x |
| Hardware handshaking/RS485 | x | x | x | x | x | x | x | x | x | x | x |
| ISO7816 | x | x | x | x | x | x | x | x | x | x | x |
| LIN | x | x | x | x | x | x | x | x | x | x | x |
| IrDA | x | x | x | x | x | x | x | x | x | x | x |
| Manchester | x | x | x | x | x | x | x | x | x | x | x |
| Asynchronous partial wake-up | x | x | x | x | x | x | x | x | x | x | x |
| FIFO size: 16 bytes | x | x | x | x | x | x | x | x | x | x | x |
| SPI | 4 CS | x | – | – | x | – | – | x | – | – | x | – |
| Asynchronous partial wake-up | x | x | x | x | x | x | x | x | x | x | x |
| FIFO size: 16 bytes | x | x | x | x | x | x | x | x | x | x | x |