When 10-bit addressing is enabled by the Ten Bit Addressing Enable bit in the Address register (ADDR.TENBITEN=1) and the Address bit field ADDR.ADDR is written, the two address bytes will be transmitted, see 10-bit Address Transmission for a Read Transaction. The addressed client acknowledges the two address bytes, and the transaction continues. Regardless of whether the transaction is a read or write, the host must start by sending the 10-bit address with the direction bit (ADDR.ADDR[0]) being zero.
If the host receives a NACK after the first byte, the Write Interrupt flag will be raised and the STATUS.RXNACK bit will be set. If the first byte is acknowledged by one or more clients, then the host will proceed to transmit the second address byte and the host will first see the Write Interrupt flag after the second byte is transmitted. If the transaction direction is read-from-client, the 10-bit address transmission must be followed by a repeated start and the first 7 bits of the address with the read/write bit equal to '1'.
address[9:8]
1'.
ADDR.TENBITEN must be cleared (can be written simultaneously with ADDR).