21.4.2 Clocks
The MCLK bus clock (CLK_MCLK_APB) can be enabled and disabled in the Main Clock module, and the default state of CLK_MCLK_APB can be found in the Peripheral Clock Masking section. If this clock is disabled, it can only be re-enabled by a reset.
The Generic Clock GCLK_MAIN is required to generate the Main Clocks. GCLK_MAIN is configured in the Generic Clock Controller, and can be re-configured by the user if needed.