28.6.2.1 Initialization
Before enabling the ADC, the asynchronous clock source must be selected and enabled, and the ADC reference must be configured. The first conversion after the reference is changed must not be used. All other configuration registers must be stable during the conversion. The source for GCLK_ADC is selected and enabled in the System Controller (SYSCTRL). Refer to SYSCTRL – System Controller for more details.
When GCLK_ADC is enabled, the ADC can be enabled by writing a one to the Enable bit in the Control Register A (CTRLA.ENABLE).