25.4.9.1 Period Match and Slow Clock
When using the prescaler, the user software can change the value of the period register faster than one timer period.
Figure 25-8 shows that when the counter is operating with an 8x prescale and PRx is written before the end of the prescaler rollover, a period match is not detected and an interrupt is not generated. In this case, the timer will continue running until a compare match occurs between TMRx and the new value M. If M is lower than the original period of N, the timer will run all the way to 0xFFFF_FFFF and roll over to 0x0000_0000.