5.7.5 I/O Configuration (IOC)

The IO Configuration (IOC) bit is a read/write bit in Status Register 2 that enables Quad SPI and QPI operation. When IOC = 0, the /WP and /HOLD pin functions are enabled. When IOC = 1, the Quad SIO2 and SIO3 pins are enabled, and the /WP and /HOLD functions are disabled.

The IOC bit must be set to 1 before issuing the Enter QPI (38h) command to switch the device from Standard, Dual or Quad SPI mode into QPI mode. Otherwise, the command is ignored. Once the device enters QPI mode, the IOC bit remains set to 1. While operating in QPI mode, the Write Status Register command cannot change the IOC bit from 1 to 0.
Note: If the /WP or /HOLD pins are tied directly to the power supply or ground during Standard SPI or Dual SPI operation, the IOC bit must not be set to 1.